Hydroxyzine and trazodone

Trazodone can be lethal if more then the prescribed dose is taken, but instances are rare, according to MedlinePlus. The average dose for an outpatient adult ranges from 150 millig...

The usual hydroxyzine dose for adults with sleep problems is 50 mg per day, administered 30 minutes before bedtime. For doxylamine, the typical dose for insomnia is 25 mg per day, also taken 30 minutes before bed. Hydroxyzine and doxylamine haven’t been tested for long-term use in cases of insomnia."Oh excuse me, my oven was calling." Some of the same engineers and designers who worked on iPhones, PowerBooks, and Beats by Dre have now turned their attention to the kitchen. A ...Atypical antidepressants are safe for most people. However, in some circumstances they can cause problems. For example: Bupropion should not be used by people who have a seizure disorder or an eating disorder such as bulimia or anorexia.; Esketamine can cause serious side effects and must be administered by a psychiatrist …14-C Urea breath test: Drug information; Abacavir and lamivudine: Drug information; Abacavir, lamivudine, and zidovudine: Drug information; Abacavir: Drug informationGet ratings and reviews for the top 11 pest companies in Caseyville, IL. Helping you find the best pest companies for the job. Expert Advice On Improving Your Home All Projects Fea...

Synonyms of this drug are atarax, durrax, and vistaril. ... Hydroxyzine (Vistaril™) is a first-generation ... trazodone, 32, and nefazodone, 33, are used to ...OBJECTIVE: Polypharmacy is common in the treatment of refractory bipolar disorder. The purpose of this article is to review the safety and efficacy of mood stabilizers in combinations. METHOD: A manual and computer (MEDLINE) search was performed for combinations of the most commonly used mood-stabilizing agents. RESULTS: The …The potential for adverse effects with hydroxyzine alone is noteworthy. Drowsiness and dizziness are fairly common, along with anticholinergic effects like dry mouth, urinary retention, and constipation. Less common but much more serious is the potential for cardiac QT-prolongation, which can precipitate serious heart rhythm problems. Hydroxyzine is an antihistamine which treats allergies, but has the sleepy qualities like a night time cold over the counter medicine would have. The trazodone doesn’t knock me out, but makes it easier to fall asleep. I’ve used both to help insomnia/ sleep paralysis. 3. Reply. Share. SessionWitty534. • 3 yr. ago. Applies to: trazodone. Alcohol can increase the nervous system side effects of traZODone such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with traZODone.traZODone venlafaxine. Applies to: trazodone and Effexor (venlafaxine) Using traZODone together with venlafaxine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive ...Hydroxyzine was really similar to Trazodone for me. Unfortunately, because of some side effects with Trazodone, I had to stop taking it – but Hydroxyzine honestly feels very similar. Trazodone, in my experience, had a higher sedative effect for helping with sleep- but hydroxyzine’s anxiolytic (anti-anxiety) effect has been greater.

Trazodone, in particular, is frequently preferred and used in psychiatric practice. Its efficacy has mainly been demonstrated in adults with psychiatric disorders (Table 1). Trazodone is a 5-HT2A/C antagonist and is one of the most sedating antidepressants with significant morning hangover effect.Preoperative Sedation. 0.6 mg/kg PO. 0.5-1.1 mg/kg IM. Anxiety. Symptomatic relief of anxiety associated with psychoneurosis and as adjunct in organic disease states. 50-100 mg PO divided q6hr or 50-100 mg IM divided q4-6hr. Continuation of therapy for >4 months has not been studied; reassess need for therapy periodically.Mar 2, 2024 · In children without a comorbid psychiatric diagnosis, alpha-blockers, hydroxyzine, and trazodone were the most common medications; in older youth, trazodone was the most common medication followed by hydroxyzine, z-drugs, and SSRIs. Sleep and related prescription medications were more commonly dispensed in those with psychiatric comorbidities. Prescribing Guidelines for Pediatric Insomnia - Nationwide Children's ...Antidepressants, like Prozac and trazodone. Symptoms could range from mild sleepiness to difficulty waking up or unsteadiness with walking. Severe degrees are …14-C Urea breath test: Drug information; Abacavir and lamivudine: Drug information; Abacavir, lamivudine, and zidovudine: Drug information; Abacavir: Drug information

Snapchat purple circle around bitmoji.

Hydroxyzine. Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is an antihistamine medication. [8] It is used in the treatment of itchiness, insomnia, anxiety, and nausea, including that due to motion sickness. [8] It is used either by mouth or injection into a muscle. [8]OBJECTIVE: While trazodone is approved for the treatment of depression, the off-label use of this medication for insomnia has surpassed its usage as an antidepressant. In this systematic review, we examined the evidence for the efficacy and safety of trazodone for insomnia. METHODS: A literature search was conducted using … Applies to: hydroxyzine. Alcohol can increase the nervous system side effects of hydrOXYzine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with hydrOXYzine. Applies to: Benadryl (diphenhydramine) and hydroxyzine. Using diphenhydrAMINE together with hydrOXYzine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems.Apr 21, 2017 · Hydroxyzine was found to block peak hERG channel tail currents in a concentration‐dependent manner, with an IC 50 of 0.39 μmol/L at near‐physiological temperature (n = 4; Fig. 1). Inhibitory effects of hydroxyzine were also observed for specific voltage‐gated sodium and calcium cardiac ion channels (Nav1.5 and Cav1.2; Fig. 1). These ... Hydroxyzine (Oral) received an overall rating of 5 out of 10 stars from 36 reviews. See what others have said about Hydroxyzine (Oral), including the effectiveness, ease of use and...

Jan 4, 2016 · Hydroxyzine was really similar to Trazodone for me. Unfortunately, because of some side effects with Trazodone, I had to stop taking it – but Hydroxyzine honestly feels very similar. Trazodone, in my experience, had a higher sedative effect for helping with sleep- but hydroxyzine’s anxiolytic (anti-anxiety) effect has been greater. i took trazodone and Oxycontin concurrently for several years with no major side effects. this does not mean that it is "ok," but my doctors did not voice any concerns or warn me about reporting ...Last updated on Feb 29, 2024. Uses. Warnings. Before taking. Dosage. Side effects. Interactions. FAQ. What is trazodone? Trazodone is an antidepressant that belongs to a group of drugs called serotonin receptor antagonists and reuptake inhibitors (SARIs).Conclusion · Hydroxyzine and trazodone can potentially interact with each other and cause adverse effects. · Combining these medications can increase the risk .....Aug 1, 2017 · OBJECTIVE: While trazodone is approved for the treatment of depression, the off-label use of this medication for insomnia has surpassed its usage as an antidepressant. In this systematic review, we examined the evidence for the efficacy and safety of trazodone for insomnia. METHODS: A literature search was conducted using MEDLINE/PubMed ... Feb 29, 2024 · Common trazodone side effects may include: drowsiness, dizziness, tiredness; swelling; weight loss; blurred vision; diarrhea, constipation; or. stuffy nose. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. 5 ounces of wine (12% alcohol) 1 1/2 ounces of liquor (40% alcohol) 12 ounces of beet (5% alcohol) The alcohol percent in the above drinks can certainly vary, but it gives you a good measuring stick. Therefore, if you have one drink, you want to wait at least one hour before taking trazodone. Two hours for two drinks, and so on.Oct 2, 2023 · Key Differences of Trazodone Vs. Hydroxyzine. Trazodone and hydroxyzine are both medications used to treat sleep disorders, but they work differently and have their unique advantages. Trazodone. Trazodone is an antidepressant medication that belongs to a class of drugs known as serotonin antagonists and reuptake inhibitors (SARIs). It is ... Hydroxyzine is used to help control anxiety and tension caused by nervous and emotional conditions. It can also be used to help control anxiety and produce sleep before surgery. This medicine is also used to relieve symptoms of allergic conditions (eg, chronic urticaria and atopic and contact dermatoses). Hydroxyzine is an antihistamine. Hydroxyzine is used to help control anxiety and tension caused by nervous and emotional conditions. It can also be used to help control anxiety and produce sleep before surgery. This medicine is also used to relieve symptoms of allergic conditions (eg, chronic urticaria and atopic and contact dermatoses). Hydroxyzine is an antihistamine.

Movies to watch while your mother sews socks in hell. Demons can be a little hard to define, and sometimes in horror the term is used as a catch-all for anything that isn’t a ghost...

Trazodone Interactions. There are 647 drugs known to interact with trazodone, along with 8 disease interactions, and 1 alcohol/food interaction.Of the total drug interactions, 136 are major, 496 are moderate, and 15 are minor.The dangers of Trazodone · Wellbutrin Withdrawal · Barbiturates Overdose and Withdrawal · Barbiturates · Duloxetine · How to Stop Taking Citalopr...Trazadone and mirtazapine both made my insomnia even worse. I stayed up like 2 days straight from 100 mg Trazodone and felt really weird. Seroquel wouldn't work unless I took 100- 200mg and then even if I slept 8-10 hours I was … Using traZODone together with venlafaxine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea ... Frequently used medications include temazepam, diphenhydramine, quetiapine, and trazodone. We have found hydroxyzine, 25 mg to 100 mg nightly, to …Jul 1, 2017 · Hydroxyzine: 50 to 100: 2: 20: $4: Not recommended: Antipsychotics: ... However, the evidence for trazodone is weak, and it should not be considered as first-line therapy. 38 In addition to ... traZODone hydrOXYzine. Applies to: trazodone and Vistaril (hydroxyzine) Using traZODone together with hydrOXYzine can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a rare side effect. You may be more susceptible if you have a heart condition called congenital long QT syndrome ...Objective: Despite lack of evidence, various pharmacological agents are judiciously used to manage anxiety in avoidant restrictive food intake disorder (ARFID). We aimed to explore the effectiveness of selective serotonin reuptake inhibitors (SSRIs), either alone or in combination with hydroxyzine, in a well-defined cohort of children and adolescents with …Trazodone is a medication used in the management and treatment of major depressive disorder. It is in the serotonin-antagonist-and-reuptake-inhibitor class of medications. This activity reviews the indications, action, and contraindications for trazodone as a valuable agent in managing major depression.For treating anxiety, you’ll likely start with a total daily dosage of 50 mg to 100 mg of hydroxyzine, taken in divided doses. This means you’ll take 12.5-mg to 25-mg doses two to four times ...

Vusxx vs vmfxx.

Eazy the block captain vs reed dollaz.

Oct 3, 2023 · The potential for adverse effects with hydroxyzine alone is noteworthy. Drowsiness and dizziness are fairly common, along with anticholinergic effects like dry mouth, urinary retention, and constipation. Less common but much more serious is the potential for cardiac QT-prolongation, which can precipitate serious heart rhythm problems. The only interaction between trazodone and hydroxyzine is that they both can cause sedation and drowsiness, and so the two may have an additive effect. Yes, that's fine, they just automatically offer the phone call, we can keep messaging here. Understand, so I I put some time like an hour between the Traz and hydroxyzine it will be ok..Do not take trazodone with a monoamine oxidase (MAO) inhibitor (eg, isocarboxazid [Marplan®], linezolid (Zyvox®), methylene blue, phenelzine [Nardil®], selegiline [Eldepryl®], tranylcypromine [Parnate®]). Do not start taking trazodone during the 2 weeks after you stop a MAO inhibitor and wait 2 weeks after stopping trazodone before you ...More about Vistaril ( hydroxyzine ) Ratings & Reviews. Trazodone has an average rating of 6.3 out of 10 from a total of 1410 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 31% reported a negative effect. Vistaril has an average rating of 5.6 out of 10 from a total of 233 ratings on Drugs.com. 45% of reviewers reported ... traZODone escitalopram. Applies to: trazodone and Lexapro (escitalopram) Using escitalopram together with traZODone can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive ... Patients with a history of heart disease or those who exceed the recommended dosage may experience unwanted reactions like heart palpitations. A recent study reported that out of 47,188 people who experienced unwanted reactions to hydroxyzine, about 393 (0.83%) had heart palpitations, implying that it’s a rare adverse reaction.macOS doesn’t have a built-in utility to adjust the volume output for individual apps—but there's a workaround. When you’re trying to listen to audio using your MacBook—whether you...Patients were excluded if requiring concomitant medication with the exception of trazodone, mirtazapine, or hydroxyzine 25 mg. All patients were on SSRI therapy for a minimum of 2 months (n = 9 on sertraline, n = 8 on fluoxetine, n = 8 on escitalopram, n = 7 on citalopram, and n = 4 on paroxetine).Cognitive impairment: In addition to making someone sleepy, Z drugs can cause loss of balance and reduced mental alertness, which may make someone prone to falls or other inadvertent injury. Dependence: People can become addicted to Z drugs, leading them to take them for longer or at higher doses than indicated.traZODone vilazodone. Applies to: trazodone and Viibryd (vilazodone) Using traZODone together with vilazodone can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive ...Cognitive impairment: In addition to making someone sleepy, Z drugs can cause loss of balance and reduced mental alertness, which may make someone prone to falls or other inadvertent injury. Dependence: People can become addicted to Z drugs, leading them to take them for longer or at higher doses than indicated.Exercise and the Glycogen-Lactic Acid System - When you exercise, you're using your muscles to create motion. The body has an incredibly complex set of processes to meet the demand... ….

Prescribing Guidelines for Pediatric InsomniaDry mouth, headache, constipation, diarrhea, and sexual dysfunction. Trazodone may cause a discontinuation syndrome if abruptly stopped, symptoms include anxiety, agitation, and sleep disturbances. When the time comes to withdraw trazodone, the dosage should be tapered off slowly under a doctor's advice.Do not take trazodone with a monoamine oxidase (MAO) inhibitor (eg, isocarboxazid [Marplan®], linezolid (Zyvox®), methylene blue, phenelzine [Nardil®], selegiline …Oct 2, 2023 · Key Differences of Trazodone Vs. Hydroxyzine. Trazodone and hydroxyzine are both medications used to treat sleep disorders, but they work differently and have their unique advantages. Trazodone. Trazodone is an antidepressant medication that belongs to a class of drugs known as serotonin antagonists and reuptake inhibitors (SARIs). It is ... Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is an antihistamine medication. It is used in the treatment of itchiness, insomnia, anxiety, and nausea, including that due to motion sickness. It is used either by mouth or injection into a muscle.. Common side effects include sleepiness, headache, and a dry mouth. Serious …Medications that raise serotonin levels. One way trazodone works is by …False-positive results for amphetamine and methamphetamine were the most commonly reported. False-positive results for methadone, opioids, phencyclidine, barbiturates, cannabinoids, and benzodiazepines were also reported in patients taking commonly used medications. The most commonly used tests to screen urine for drugs of abuse are ...Hydroxyzine was really similar to Trazodone for me. Unfortunately, because of some side effects with Trazodone, I had to stop taking it – but Hydroxyzine honestly feels very similar. Trazodone, in my experience, had a higher sedative effect for helping with sleep- but hydroxyzine’s anxiolytic (anti-anxiety) effect has been greater.Please know that the combination of trazodone and hydroxyzine can cause harmful interactions, including sedation, dizziness, and drowsiness, leading to the increased likelihood of falls, cognitive impairment, and other similar issues. Hydroxyzine and trazodone, This study evaluated the effect of 3 doses of a trazodone hydrochloride 6% oral drops solution on the QT interval of healthy volunteers. Subjects were randomly assigned to receive a single dose of trazodone 20 mg, 60 mg, and 140 mg, moxifloxacin 400 mg, and trazodone‐matched placebo in 5 periods separated by 7‐day washouts, …, traZODone vilazodone. Applies to: trazodone and Viibryd (vilazodone) Using traZODone together with vilazodone can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive ..., The study uses data from the FDA. It is based on trazodone hydrochloride and hydroxyzine hydrochloride (the active ingredients of Trazodone hydrochloride and Hydroxyzine, respectively), and Trazodone hydrochloride and Hydroxyzine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered., Feb 26, 2023 · Patients were excluded if requiring concomitant medication with the exception of trazodone, mirtazapine, or hydroxyzine 25 mg. All patients were on SSRI therapy for a minimum of 2 months ( n = 9 on sertraline, n = 8 on fluoxetine, n = 8 on escitalopram, n = 7 on citalopram, and n = 4 on paroxetine). , Applies to: trazodone and Geodon (ziprasidone) Using ziprasidone together with traZODone is not recommended. Combining these medications can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. You may be more susceptible if you have a heart condition ..., Buspirone has an average rating of 5.9 out of 10 from a total of 1334 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 36% reported a negative effect. Hydroxyzine has an average rating of 5.7 out of 10 from a total of 1375 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 36% reported a negative ..., traZODone vilazodone. Applies to: trazodone and Viibryd (vilazodone) Using traZODone together with vilazodone can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive ..., Trazodone is a prescription drug used to treat depression and sleep disorders like insomnia.When using trazodone for sleep, the drug is given at low doses—typically between 25 to 100 milligram (mg)—which reduces the risk of drug tolerance and daytime sleepiness. For some people, even lower doses may prove …, Hydroxyzine is an antihistamine which treats allergies, but has the sleepy qualities like a night time cold over the counter medicine would have. The trazodone doesn’t knock me out, but makes it easier to fall asleep. I’ve used both to help insomnia/ sleep paralysis. 3. Reply. Share. SessionWitty534. • 3 yr. ago., Get ratings and reviews for the top 11 gutter guard companies in Chevy Chase, MD. Helping you find the best gutter guard companies for the job. Expert Advice On Improving Your Home..., Buspirone has an average rating of 5.9 out of 10 from a total of 1334 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 36% reported a negative effect. Hydroxyzine has an average rating of 5.7 out of 10 from a total of 1375 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 36% reported a negative ..., Trazodone is a prescription drug for treating depression. It comes as an oral tablet and as a generic drug only. Learn about side effects, warnings, dosage, and more., How it works. Alternatives. Pregnancy. Birth control needs. Breastfeeding. Cost. How to take. Precautions. Overdose. Withdrawal and dependence. Expiration. What is hydroxyzine? Hydroxyzine is a..., This study evaluated the effect of 3 doses of a trazodone hydrochloride 6% oral drops solution on the QT interval of healthy volunteers. Subjects were randomly assigned to receive a single dose of trazodone 20 mg, 60 mg, and 140 mg, moxifloxacin 400 mg, and trazodone‐matched placebo in 5 periods separated by 7‐day washouts, …, Trazodone Interactions. There are 647 drugs known to interact with trazodone, along with 8 disease interactions, and 1 alcohol/food interaction.Of the total drug interactions, 136 are major, 496 are moderate, and 15 are minor., Trazodone. Another medication frequently used is Trazodone, which is one of the most popular medications used to treat insomnia. Trazodone in low doses (50mg to 100mg) can provide the side effect of sedation without this effect carrying over to the next day. ... Hydroxyzine and Vistaril. The use of Hydroxyzine or Vistaril is often added to ..., Trazodone is not a benzodiazepine, according to Drugs.com. Trazodone is an antidepressant that treats chemical imbalances in the brain that are known to lead to major depressive di..., Yes the grogginess do subside within a few days. I took hydroxyzine and had the same feeling but went away within 2 days. If grogginess do continue overtime, you can try taking it earlier at night (around 7-8pm). Tyrese. Or as masso said; perhaps you need a dose adjustment., Using hydrOXYzine together with methocarbamol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications ..., Dry mouth, headache, constipation, diarrhea, and sexual dysfunction. Trazodone may cause a discontinuation syndrome if abruptly stopped, symptoms include anxiety, agitation, and sleep disturbances. When the time comes to withdraw trazodone, the dosage should be tapered off slowly under a doctor's advice., I told my primary care doctor my sleeping was still interrupted for various reasons in the night. Hydroxyzine is also a new medication I just started a few days ago. But my PC doctor prescribed me Trazadone to help me sleep at night. I am reluctant to take this because they say their is an interraction between them related to heart issues., Trazodone. Another medication frequently used is Trazodone, which is one of the most popular medications used to treat insomnia. Trazodone in low doses (50mg to 100mg) can provide the side effect of sedation without this effect carrying over to the next day. ... Hydroxyzine and Vistaril. The use of Hydroxyzine or Vistaril is often added to ..., Alaska Airlines is piling on in Los Angeles with eight new routes this fall and winter in what it sees as a "down payment" on future growth at the Southern California hub. There ar..., Hydroxyzine was really similar to Trazodone for me. Unfortunately, because of some side effects with Trazodone, I had to stop taking it – but Hydroxyzine honestly feels very similar. Trazodone, in my experience, had a higher sedative effect for helping with sleep- but hydroxyzine’s anxiolytic (anti-anxiety) effect has been greater. I think ..., Preoperative Sedation. 0.6 mg/kg PO. 0.5-1.1 mg/kg IM. Anxiety. Symptomatic relief of anxiety associated with psychoneurosis and as adjunct in organic disease states. 50-100 mg PO divided q6hr or 50-100 mg IM divided q4-6hr. Continuation of therapy for >4 months has not been studied; reassess need for therapy periodically., We have found that hydroxyzine is effective, well tolerated, and has fewer side effects than other commonly used hypnotics. Many physicians prescribe hypnotics for hospitalized patients with insomnia. Frequently used medications include temazepam, diphenhydramine, quetiapine, and trazodone., More about Vistaril ( hydroxyzine ) Ratings & Reviews. Trazodone has an average rating of 6.3 out of 10 from a total of 1410 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 31% reported a negative effect. Vistaril has an average rating of 5.6 out of 10 from a total of 233 ratings on Drugs.com. 45% of reviewers reported ..., I told my primary care doctor my sleeping was still interrupted for various reasons in the night. Hydroxyzine is also a new medication I just started a few days ago. But my PC doctor prescribed me Trazadone to help me sleep at night. I am reluctant to take this because they say their is an interraction between them related to heart issues., Trazadone and Hydroxyzine . I have been dealing with insomnia for a really long time and was prescribed hydroxyzine (50mg), but it did nothing for me, so my doctor prescribed me Tradazone (50mg) and it didn’t work either. ... i'm on 100mg of trazodone. that's been my dose over a year now. always works for me., Quantum suicide is a form of thought experiment that is related to the field of quantum physics. Learn about the concepts behind the quantum suicide theory. Advertisement ­­A man s..., Mirtazapine has an average rating of 6.8 out of 10 from a total of 2024 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 21% reported a negative effect. Trazodone has an average rating of 6.3 out of 10 from a total of 1410 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 31% reported a negative ..., Applies to: trazodone and tizanidine. Using traZODone together with tiZANidine can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a rare side effect. You may be more susceptible if you have a heart condition called congenital long QT syndrome, other cardiac diseases ..., Hydroxyzine is an antihistamine that also does some stuff to serotonin, and trazodone is an antidepressant and serotonin antagonist that's also an antihistamine. After looking at the wiki pages for both, they seem pretty similar in terms of effects. For trazodone it says it is mostly a 5-HT2a antagonist at low doses.