Doxylamine succinate and diphenhydramine

8 results for "doxylamine succinate" Results. Benadryl Allergy Relief Capsules - Fast-Acting Antihistamine Capsules - Starts to Work in 15 Minutes - 12 Capsules. 4.6 out of 5 stars 6,612. 1K+ bought in past month.

Doxylamine succinate and diphenhydramine. Doxylamine is a medication used to manage and treat nausea and vomiting of pregnancy (NVP), allergic rhinitis, and insomnia. It is in the first-generation histamine receptor H1 antagonist class of medications. In the USA, it is available as an over-the-counter medication. This activity reviews the indications, action, and contraindications for doxylamine as a valuable agent in managing nausea ...

RXZELL Sleep Aid, Diphenhydramine HCl 50mg, 220 Softgels - Fall Asleep Faster, Deeper Restful Sleeping, Non Habit-Forming ... WELMATE | Doxylamine Succinate 25mg | Nighttime Sleep Aid | Safe & Effective | Non-Habit Forming | Sleep Aids for Adults & Children | for Women & Men | Made in USA | 200 Tablets.

What is this medication? DOXYLAMINE (dox IL a meen) treats occasional insomnia. It helps you go to sleep. It belongs to a group of medications called antihistamines. This …Doxylamine. Like diphenhydramine, doxylamine – also known as doxylamine succinate – is a first-generation antihistamine that can produce sedative effects. Doxylamine can serve as a short-term treatment for insomnia Trusted Source Medline Plus MedlinePlus is an online health information resource for patients and their …Sep 24, 2017 · I had been using diphenhydramine but it had a tendency to wear off after about 5 hours. I’m the type that needs eight good hours of sleep. I happened across the Kirkland sleep aid doxylamine succinate you mentioned. I had never tried it before. I tried it for the first night and was extremely sleepy and groggy the next day. In terms of dose equivalence, I was surprised to see in e Table 1 the suggestion that a minimum effective daily dose in older people for diphenhydramine is "50 mg", but of dimenhydrinate is "200 mg". Dimenhydrinate, the 8-chlorotheophylline salt of diphenhydramine, consists of over 50% diphenhydramine by weight. Doxylamine and diphenhydramine are Food and Drug Administration (FDA) approved antihistamines used to treat insomnia, motion sickness, hay fever, and common cold symptoms, among other uses. As commonly used medications, doxylamine and diphenhydramine, administered to adults and children, are available in generic and …Both doxylamine (Unisom) and diphenhydramine (Benadryl, ZzzQuil) can be used for short-term sleep problems for up to 2 weeks. They work similarly and they have similar side effects. Doxylamine stays in your system longer than diphenhydramine. So it may be …To investigate the level of evidence supporting the use of common over-the-counter (OTC) agents (diphenhydramine, doxylamine, melatonin, and valerian) for occasional …

Each Unisom SleepMelt tablet contains 25 mg of diphenhydramine. The typical Unisom SleepGel dosage is 2 tablets (50 mg) about 30 minutes before bedtime as needed. Don’t take more than 2 tablets daily. Speak with your healthcare provider if you’ve been taking Unisom SleepMelts for 2 weeks in a row.RXZELL Sleep Aid, Diphenhydramine HCl 50mg, 220 Softgels - Fall Asleep Faster, Deeper Restful Sleeping, Non Habit-Forming ... WELMATE | Doxylamine Succinate 25mg | Nighttime Sleep Aid | Safe & Effective | Non-Habit Forming | Sleep Aids for Adults & Children | for Women & Men | Made in USA | 200 Tablets.Doxylamine succinate works in a similar way to Benadryl, which is a branded medicine that contains another antihistamine called diphenhydramine 15. Like doxylamine succinate, diphenhydramine can be used to treat allergic reactions and act as a short-term sleep aid.scientists have discovered any otc sleep aids that have something other than diphenhydramine?: Yes: Melatonin is an over the counter substance that many people take ... What is benadryl (diphenhydramine) (and also the anti-histamine doxylamine succinate, both sleeping aids)? A doctor has provided 1 answer. A member asked:The addition of KLM and its Amsterdam flights give Austin's fast-growing airport its fourth nonstop route to Europe. Austin has landed another high-profile international route, thi...

Key takeaways: Over-the-counter (OTC) antihistamines are commonly used to treat allergies. Some can also treat nausea and help you sleep. There are different categories (or generations) of OTC antihistamines. First-generation antihistamines include diphenhydramine (Benadryl). Second- and third-generation antihistamines include …Some, like doxylamine succinate and diphenhydramine, are used in nighttime cold medicine because they make you drowsy. Antihistamines can also cause dizziness, dry mouth, and blurry vision. Taking multiple antihistamines at once can increase these side effects.Doxylamine, while effective, is less commonly used for allergies and more for its sedative properties in aiding sleep. 8. The duration of action varies slightly between the two. Diphenhydramine typically has a shorter duration of action, requiring more frequent dosing. Doxylamine, with a longer half-life, can provide longer-lasting relief but ...We’re T-minus 24 hours until the TechCrunch Disrupt early bird flies south and takes up to $1,300 in savings with it. If you’re serious about realizing your startup dreams, you nee...Sep 24, 2017 · I had been using diphenhydramine but it had a tendency to wear off after about 5 hours. I’m the type that needs eight good hours of sleep. I happened across the Kirkland sleep aid doxylamine succinate you mentioned. I had never tried it before. I tried it for the first night and was extremely sleepy and groggy the next day. Diuretics cause your body to release more urine. Avoid drinks that may have a diuretic effect. These include: alcohol. coffee. soda. other caffeinated beverages. Avoiding or reducing intake of ...

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Aug 24, 2023 · Doxylamine and pyridoxine side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Common side effects of doxylamine and pyridoxine may include: drowsiness. This is not a complete list of side effects and others may occur. Doxylamine Interactions. There are 311 drugs known to interact with doxylamine, along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 18 are major, 292 are moderate, and 1 is minor. SleepTabs with Doxylamine succinate help you fall asleep an average of 33% faster.** For adults and children 12 years of age and older, one tablet should be taken 30 minutes before going to bed or as directed by a healthcare professional.Doxylamine Succinate & Phenylephrine HCl. These tablets offer another combination of an antihistamine and a nasal decongestant. Phenylephrine remains as the decongestant, while Doxylamine Succinate offers its antihistamine properties to dry up the eyes/nose/throat and reduce sneezing. Protect Yourself and Loved Ones This Cough …Although there aren’t any recommended sleep aids specifically for people with diabetes, Kelley Champ Crumpler, a diabetes nurse educator and the wife of an endocrinologist, primarily recommends ...Doxylamine, while effective, is less commonly used for allergies and more for its sedative properties in aiding sleep. 8. The duration of action varies slightly between the two. Diphenhydramine typically has a shorter duration of action, requiring more frequent dosing. Doxylamine, with a longer half-life, can provide longer-lasting relief but ...

SleepTabs with Doxylamine succinate help you fall asleep an average of 33% faster.** For adults and children 12 years of age and older, one tablet should be taken 30 minutes before going to bed or as directed by …The type of drug taken also mattered. People who were on a long-acting benzodiazepine like diazepam (Valium) or flurazepam (Dalmane) were at greater risk than those on a short-acting one like triazolam (Halcion), lorazepam (Ativan), alprazolam (Xanax), or temazepam (Restoril). Why these drugs have a stronger effect in older people.Scottish Medicines Consortium (SMC) decisions. SMC No. SMC2140. Doxylamine succinate and pyridoxine hydrochloride (Xonvea®) for the treatment of nausea and vomiting of pregnancy in women who do not respond to conservative management (May 2019) Not recommended.I've been alternating with 50mg diphenhydramine + 3mg melatonin, and then the next night 25mg doxylamine succinate + 3mg melatonin. I've been doing this for four years. This allows me to fall asleep at a normal time (around 11ish) as opposed to 4am if up to my body.Phenylephrine hydrochloride, dextromethorphan hydrobromide, pseudoephedrine hydrochloride, guaifenesin, chlorpheniramine maleate, brompheniramine maleate, diphenhydramine hydrochloride, and doxylamine succinate were the common active ingredients, with all available OTC sinonasal remedies consisting of 1 or more of these ingredients.SleepTabs with Doxylamine succinate help you fall asleep an average of 33% faster.** For adults and children 12 years of age and older, one tablet should be taken 30 minutes before going to bed or as directed by a healthcare professional.Always check the labels on substances such as these, as sometimes diphenhydramine may be combined with other medications like non-steroidal anti-inflammatories (ibuprofen or naproxen) that can cause stomach ulcers and kidney injury. Doxylamine is an antihistamine very similar to diphenhydramine with similar concerns. …Diphenhydramine is known for its sedating effects and is often used to treat occasional sleeplessness. On the other hand, Doxylamine is generally considered to be more potent and longer-lasting, making it a preferred choice for individuals with chronic insomnia. Additionally, Diphenhydramine is more likely to cause drowsiness the next day ...

In patients older than 12 years of age: Nyquil™ (doxylamine succinate), Tavist (clemastine fumarate), chlorpheniramine maleate or Benadryl® (diphenhydramine) may help relieve symptoms, although these may cause sleepiness. Chlorpheniramine maleate is the least sedating of the products listed above.

Oral. Doxylamine succinate 10 mg/pyridoxine hydrochloride 10 mg delayed-release tablets (Diclegis ): Initially, 2 tablets at bedtime. If symptoms the next day are adequately controlled, continue this dosage daily at bedtime. If symptoms persist into the afternoon of day 2, add 1 tablet in the morning on day 3.Jun 5, 2023 · Doxylamine is a medication used to manage and treat nausea and vomiting of pregnancy (NVP), allergic rhinitis, and insomnia. It is in the first-generation histamine receptor H1 antagonist class of medications. In the USA, it is available as an over-the-counter medication. This activity reviews the indications, action, and contraindications for doxylamine as a valuable agent in managing nausea ... To investigate the level of evidence supporting the use of common over-the-counter (OTC) agents (diphenhydramine, doxylamine, melatonin, and valerian) for occasional …Dec 1, 2018 ... "People taking sleep aids are essentially taking Benadryl [diphenhydramine]. They don't realize that's what most sleep aids are," said Dr ...We would like to show you a description here but the site won’t allow us.Wolfspeed Inc. (WOLF), Marcus & Millichap Inc. (MMI) and Nicolet Bankshares Inc. (NIC) are three bearish-looking stocks that you should think about shorting this week, tech...Both doxylamine succinate and Diphenhydramine belong to the antihistamine group of medicines. Histamine is a chemical neurotransmitter released in the body in response to …Doxylamine succinate 350mg trip report. I know this isn’t the same as DPH, but there isn’t a subreddit for doxylamine, nor is there much information on recreational use for it. After taking the 350mg, I felt it kick in about 35 minutes later. There was a strong body high similar to DPH, but my throat felt felt like it was folded in half.Moderation: Doxylamine and Diphenhydramine are both available over-the-counter, both have similar anti-histamine properties, used as sleep aids to help cause drow... Read More. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help. 4.4k views Reviewed >2 years ago.The addition of KLM and its Amsterdam flights give Austin's fast-growing airport its fourth nonstop route to Europe. Austin has landed another high-profile international route, thi...

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I've been alternating with 50mg diphenhydramine + 3mg melatonin, and then the next night 25mg doxylamine succinate + 3mg melatonin. I've been doing this for four years. This allows me to fall asleep at a normal time (around 11ish) as opposed to 4am if up to my body.It was only when the patient took an antihistamine for a cheese allergy in June of 2020 that she suddenly felt better. She started taking 50 milligrams of diphenhydramine (a common over-the-counter antihistamine, often sold in the US as Benadryl) daily, but eventually took the news to her doctor, who prescribed a different medication to try and …Nyquil adds doxylamine succinate to help you sleep, DayQuil adds phenylephrine as a decongestant. Triaminic Cold and Cough contains the active ingredients phenylephrine and diphenhydramine. It can ...Applies to: Zoloft (sertraline) and doxylamine. Using sertraline together with doxylamine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of ...Dec 23, 2004 · Didn`t found anything specific about Diphenhydramine + Doxylamine, but several sources inform that they have mixed - although mostly under medical supervision - several antihistamines. Some sold Endproducts even are a mix by themselves. Obs.: both Diphenhydramine and Doxylamine are mentionend, among several other substances. The usual adult dose of diphenhydramine is 50mg, whereas the dose for doxylamine succinate is 25mg, so bear that in mind, Doxylamine succinate is first generation antihistamine just like diphenhydramine (Benadryl) and has pretty much all the same side effects - dry mouth, next day “hangover,” a nice relief from seasonal allergies, mild ... We would like to show you a description here but the site won’t allow us. The argument: exclusive student groups breed elitism, sexism, alcohol abuse, and other problems by their very nature. Things are changing fast at America’s oldest university. In a ...Both Diphenhydramine and Doxylamine Succinate have their own pros and cons when it comes to helping you sleep better at night. In most cases, however, Doxylamine Succinate tends to be more effective and acts faster than Diphenhydramine without the same side effects like dry mouth or drowsiness that often come with using Diphenhydramine.Novell GroupWise is a suite of productivity applications featuring an email client, group calendars, instant messaging and contact management. The program is designed for the offic...We would like to show you a description here but the site won’t allow us.Do Doxylamine Succinate and Diphenhydramine increase each other's tolerance? They're both antihistamines, yet differently named drugs. So, if I take like 4 Nyquil caps ( Doxylamine Succinate) one night for a few days, then switch to Zzzquil caps (Diphenhydramine), would the Nyquil have significant tolerance effect on the Zzzquil? ….

Always check the labels on substances such as these, as sometimes diphenhydramine may be combined with other medications like non-steroidal anti-inflammatories (ibuprofen or naproxen) that can cause stomach ulcers and kidney injury. Doxylamine is an antihistamine very similar to diphenhydramine with similar concerns. …It was only when the patient took an antihistamine for a cheese allergy in June of 2020 that she suddenly felt better. She started taking 50 milligrams of diphenhydramine (a common over-the-counter antihistamine, often sold in the US as Benadryl) daily, but eventually took the news to her doctor, who prescribed a different medication to try and … Diphenhydramine (Benadryl) Summary Doxylamine succinate (Unisom SleepTabs) is an over-the-counter antihistamine that can be taken by adults and children ages 12 years and older who are having trouble falling asleep. I was ten when my mother had her first psychotic break. It was May. I was looking forward to lazy summer days I was ten when my mother had her first psychotic break. It was May. I ...6.25 mg of doxylamine. 5 mg of phenylephrine. The typical adult dosage of NyQuil Severe is 2 pills or 30 mL by mouth every 4 hours as needed. Don’t take more than 4 doses (8 pills or 120 mL) in 24 hours. It’s important to note that the VapoCOOL version contains 10% alcohol, whereas the other flavors are alcohol free.Few times a week. Doxylamine succinate and Benadryl. I had a terrible bout of insomnia in January and February and took up to 5 59mg benadryl a night for weeks, same doxy alternating. I couldn't remember what i did a minute ago. I was dumb. I finally said im done with these forever. I knew the long term dementia issues, somehow the immediate ...doxylamine food. Applies to: doxylamine. Alcohol can increase the nervous system side effects of doxylamine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with doxylamine.Both doxylamine (Unisom) and diphenhydramine (Benadryl, ZzzQuil) can be used for short-term sleep problems for up to 2 weeks. They work similarly and they have similar side effects. Doxylamine stays in your system longer than diphenhydramine. So it may be more likely to cause next-day drowsiness. Doxylamine succinate and diphenhydramine, Policies that help pay for nursing and other care can be costly. If you decide insurance is for you, here's what to do to keep down the price. By clicking "TRY IT", I agree to rece..., Diphenhydramine or Doxylamine succinate? Just picked up both at the store today. Which one has a better chance of me falling asleep? I can’t see a doctor right now for heavy sleep meds, so over the counter it is right now. comments sorted by Best Top New Controversial Q&A Add a Comment Low ..., Benadryl (diphenhydramine) Claritin (loratadine) CoQ10 (ubiquinone) Cymbalta (duloxetine) Eliquis (apixaban) Fish Oil (omega-3 polyunsaturated fatty acids) Flonase (fluticasone nasal) Lyrica (pregabalin) Metoprolol Succinate ER (metoprolol) Metoprolol Tartrate (metoprolol) MiraLAX (polyethylene glycol 3350) Mucinex (guaifenesin), Diuretics cause your body to release more urine. Avoid drinks that may have a diuretic effect. These include: alcohol. coffee. soda. other caffeinated beverages. Avoiding or reducing intake of ..., Nov 7, 2022 · Diphenhydramine (Benadryl, Nytol, Sominex) Doxylamine (Vicks NyQuil, Tylenol Cold and Cough Nighttime) These antihistamines start to take effect in about 30 to 60 minutes and last for four to six ... , Diphenhydramine (Benadryl). Diphenhydramine is a sedating antihistamine. Side effects might include daytime drowsiness, dry mouth, constipation and urinary retention. Doxylamine (Unisom). Doxylamine is also a sedating antihistamine. Side effects are similar to those of diphenhydramine. Melatonin., INTRODUCTION. There is a greater burden of sleep difficulties (e.g., difficulty falling asleep, waking up too early) among older adults age 65 and older than any other age group in the United States (US). 1 Those experiencing sleep difficulties may seek medications to aid with their difficulties, either healthcare provider-administered psychotropic medication, 2 or …, Jul 28, 2020 · Both doxylamine succinate and Diphenhydramine are used to treat conditions like allergic conjunctivitis and allergic rhinitis, hay fever, common cold, urticaria (hives), and itching. Apart from the antihistaminic effect of doxylamine succinate and Diphenhydramine, both these medicines also exert an anticholinergic effect. , Doxylamine succinate, an oral first-generation H1-antihistamine drug is commonly used in sleep-inducing OTC mediations. A 69-year-old woman was admitted to an emergency department with a 1-day history of worsening drowsiness and confusion following ingestion of 16 tablets of 25 mg of doxylamine 48 h previously due to her recently exacerbated ..., Nyquil adds doxylamine succinate to help you sleep, DayQuil adds phenylephrine as a decongestant. Triaminic Cold and Cough contains the active ingredients phenylephrine and diphenhydramine. It can ..., little or no urinating. Common side effects of doxylamine may include: blurred vision; dry mouth, nose, or throat; constipation; or. mild dizziness or drowsiness. Side effects such as dry mouth, constipation, and confusion may be more likely in older adults. This is not a complete list of side effects and others may occur., Acetaminophen Dextromethorphan Hydrobromide Doxylamine Succinate Phenylephrine hydrochloride: Doxylamine succinate (6.25 mg/1) + Acetaminophen (325 mg/1) + Dextromethorphan hydrobromide monohydrate (10 mg/1) + Phenylephrine hydrochloride (5 mg/1) Capsule, liquid filled: Oral: Healthlife of Usa: 2017-07-07: 2017-07-07: US, Both Diphenhydramine and Doxylamine Succinate have their own pros and cons when it comes to helping you sleep better at night. In most cases, however, Doxylamine Succinate tends to be more effective and acts faster than Diphenhydramine without the same side effects like dry mouth or drowsiness that often come with using Diphenhydramine., Doxylamine succinate 350mg trip report. I know this isn’t the same as DPH, but there isn’t a subreddit for doxylamine, nor is there much information on recreational use for it. After taking the 350mg, I felt it kick in about 35 minutes later. There was a strong body high similar to DPH, but my throat felt felt like it was folded in half., The active ingredients in NyQuil are acetaminophen, dextromethorphan HBr and doxylamine succinate. NyQuil also contains a number of inactive ingredients., Jun 11, 2015 ... Doxylamine succinate is a type of antihistamine called an ethanolamine derivative antihistamine. It has a sedating effect. Before taking DOZILE., View Source, doxylamine Trusted Source Medline Plus MedlinePlus is an online health information resource for patients and their families and friends. View Source. Indicated …, Diphenhydramine (DPH) is an antihistamine and sedative mainly used to treat allergies, insomnia, and symptoms of the common cold. It is also less commonly ..., Is diphenhydramine hydrochloride and doxylamine succinate ok together? Caution Required: Both drugs have similar "mechanisms of action." therefore, the effects they produce are "additive" and, in theory, can pile up to create more effects than would be predicted if each drug were taken by itself...Almost as if 1+1=3! both drugs produce …, Benadryl. A total of 446 drugs are known to interact with Benadryl . Benadryl is in the following drug classes: anticholinergic antiemetics, anticholinergic antiparkinson agents, antihistamines, miscellaneous anxiolytics, sedatives and hypnotics . Benadryl is used to treat the following conditions: Allergic Reactions. Allergic Rhinitis. Allergies., Is diphenhydramine hydrochloride and doxylamine succinate ok together? Caution Required: Both drugs have similar "mechanisms of action." therefore, the effects they produce are "additive" and, in theory, can pile up to create more effects than would be predicted if each drug were taken by itself...Almost as if 1+1=3! both drugs produce …, 2-[(alpha)- (2-dimethylaminoethoxy)(alpha)- methylbenzyl]pyridine succinate. Doxylamine succinate is a white or almost white powder, very soluble in water and freely soluble in alcohol. Chemical Formula: C 17 H 22 N 2 O.C 4 H 6 O 4. Molecular Weight: 388.5. CAS number. 562-10-7. 7 Medicine Schedule (Poisons Standard) Schedule 3 …, The usual adult dose of diphenhydramine is 50mg, whereas the dose for doxylamine succinate is 25mg, so bear that in mind, Doxylamine succinate is first generation antihistamine just like diphenhydramine (Benadryl) and has pretty much all the same side effects - dry mouth, next day “hangover,” a nice relief from seasonal allergies, mild ..., Doxylamine, while effective, is less commonly used for allergies and more for its sedative properties in aiding sleep. 8. The duration of action varies slightly between the two. Diphenhydramine typically has a shorter duration of action, requiring more frequent dosing. Doxylamine, with a longer half-life, can provide longer-lasting relief but ..., Doxylamine causes more drowsiness than diphenhydramine. It is as effective as diphenhydramine, but the duration of effect is longer, for up to eight hours. …, In patients older than 12 years of age: Nyquil™ (doxylamine succinate), Tavist (clemastine fumarate), chlorpheniramine maleate or Benadryl® (diphenhydramine) may help relieve symptoms, although these may cause sleepiness. Chlorpheniramine maleate is the least sedating of the products listed above., Diphenhydramine is the active ingredient in Sleep Eze, Sominex, Nytol, Tylenol PM, and Unisom SleepGels; Doxylamine succinate. Doxylamine succinate is one of the most sedating antihistamines available over-the-counter (stronger than diphenhydramine). A single dose causes rapid and marked drowsiness in the vast majority of individuals., Two Benadryl 25mg tablets would be equivalent to one Unisom SleepGel 50mg capsule. Unisom SleepTabs contain a drug called doxylamine. Doxylamine is a drug that is extremely similar to Benadryl. Both are “first-generation” antihistamines. Like Benadryl, it also commonly causes drowsiness, dizziness, dry mouth, constipation, urinary retention ..., There are moments in life that hurt big. Like, really big. Moments that shatter your heart into a million pieces. Moments that make you question the point of it all.... Edit Your P..., Kirkland Signature Sleep Aid Doxylamine Succinate 25mg. This medication contains 25mg of doxylamine succinate. It is a nighttime sleep aid that claims to help you fall asleep fast. You only need one tablet per dose, and it is safe and proven effective by others who have used it. One bottle contains 96 tablets., Acetaminophen Dextromethorphan Hydrobromide Doxylamine Succinate Phenylephrine hydrochloride: Doxylamine succinate (6.25 mg/1) + Acetaminophen (325 mg/1) + Dextromethorphan hydrobromide monohydrate (10 mg/1) + Phenylephrine hydrochloride (5 mg/1) Capsule, liquid filled: Oral: Healthlife of Usa: 2017-07-07: 2017-07-07: US, little or no urinating. Common side effects of doxylamine may include: blurred vision; dry mouth, nose, or throat; constipation; or. mild dizziness or drowsiness. Side effects such as dry mouth, constipation, and confusion may be more likely in older adults. This is not a complete list of side effects and others may occur., Dec 5, 2023 · Diphenhydramine (Benadryl, Advil PM, others). Doxylamine (NyQuil Cold & Flu, Nighttime Cold & Flu Relief, others). Chlorpheniramine (Chlor-Trimeton, Alka-Seltzer Plus Cold Medicine, others). Antihistamines that make you sleepy can be useful as a sleep aid once in a while. But tolerance to the effects of these antihistamines develops quickly.